The EPA is publishing a draft list of contaminants that are currently not subject to any proposed or promulgated national primary drinking water regulations for public review and comment. These contaminants are known or anticipated to occur in public water systems and may require regulation under the SDWA in the future. The draft list provided in this document is the sixth Contaminant Candidate List (CCL) published by the Agency since the SDWA amendments of 1996. The draft Sixth Contaminant Candidate List (CCL 6 or the list) includes 75 chemicals, 4 chemical groups (disinfection byproducts (DBPs), microplastics, per- and polyfluoroalkyl substances (PFAS), and pharmaceuticals) and 9 microbes. The EPA seeks public comment on the draft CCL 6 and the process used to develop the draft CCL 6. The EPA will consider all information and comments received in response to this notice of availability for determining the final CCL 6. Comments must be received on or before 5 June 2026. POC is Thomas Lombardi, Standards and Risk Management Division, Office of Ground Water and Drinking Water; email: lombardi.thomas@epa.gov; tele: (202) 564-7653. (Federal Register 6 April 2026 [Proposed Rule] Pages 17186-17195)