The International Institute for Sustainable Laboratories (I2SL) Annual Conference and Technology Fair is a premier event focused on advancing sustainability, energy efficiency, and decarbonization in laboratories and other high-tech facilities. Scheduled for September 13–16, 2026, at Encore Boston Harbor near Boston, the conference brings together approximately 500 professionals--including laboratory owners, facility managers, architects, engineers, researchers, and sustainability leaders--to share innovative solutions and best practices. The program features more than 100 technical presentations, pre-conference workshops, facility tours, networking opportunities, and a Technology Fair with around 50 exhibitors showcasing products and services for sustainable laboratory design and operation. Key topics include energy-efficient building systems, green labs initiatives, operational optimization, emerging technologies, and strategies for reducing the environmental impact of research facilities while improving performance and resilience.