The U.S. Environmental Protection Agency (EPA) is proposing regulatory amendments to the hazardous waste manifest regulations to establish a date for sunsetting use of paper manifests in favor of electronic manifests. Phasing out paper manifests would unlock the estimated $28.5 million annual savings through decreased burden to manifest users while also increasing human health and environmental protection through better tracking of hazardous waste and greater transparency for regulators and the public. The proposed rule also introduces several conforming amendments to existing regulations. These include new registration requirements with the EPA's e-Manifest system for RCRA hazardous waste transporters, certain PCB waste generators, and PCB waste transporters. Additionally, the rule updates exception reporting requirements for very small quantity generators (VSQGs) managing hazardous waste from episodic events, as well as for healthcare facilities and reverse distributors handling hazardous waste pharmaceuticals. It also revises discrepancy reporting requirements for owners and operators of hazardous waste facilities operating under standardized permits. Lastly, the proposed rule includes four technical corrections to the import and export requirements to correct EPA's mailing address, remove obsolete text, and correct a citation associated with manifest corrections for export shipments. Comments must be received on or before 4 May 2026. POC is Bryan Groce (email:groce.bryan@epa.gov; phone: (202) 566-0339)