Medical facilities use a variety of bioactive substances to treat assorted conditions. It has only been recently that the alarm has been raised about the environmental impact of substances such as prescription and over-the counter therapeutic drugs, veterinary drugs, diagnostic agents, and ultraceuticals (e.g., vitamins.) The first consumer guidance on the disposal of prescription drugs was issued in February 2007 by the White House Office of National Drug Control Policy. EPA provides guidance and monitors the regulatory climate in relation to pharmaceuticals. For a more detailed overview of managing pharmaceutical waste the August 2008 guide published by the Healthcare Environmental Resource Center (HERC) outlines a 10-step approach for managing pharmaceutical waste.